There are approximately 7,000 rare diseases that affect 30 million Americans. That means one in ten lives with a rare disease. A condition is considered rare if it affects fewer than 200,000 people. The University of Rochester is one institute leading clinical research and therapeutic development of rare diseases. Joining this edition of Need to Know is one of the gifted minds involved in that work. Dr. Erika Augustine, Director of the Center of Human Experimental Therapeutics discusses her recent findings and an upcoming event focused on rare diseases sponsored by the University of Rochester.